How is it best - when adding new clients that I add them to the main list in Activecampaign then tag them on their interests or do I put them in 2 different lists?

ActiveCampaign is a marketing and sales automation platform that helps growing businesses meaningfully connect and engage with their customers. Its SaaS platform enables businesses to create optimized customer experiences by automating many behind the scenes processes and communicating with their customers across channels with personalized messages.